Theypromised____eachotherwhentheywenttowork.

Don'twashthosefossils!

StandardmuseumpracticecanwashawayDNA.

1.Washing,brushingandvarnishingfossils—allstandardconservationtreatmentsusedbymanyfossilhuntersandmuseumcuratorsalike—vastlyreducesthechancesofrecoveringancientDNA.

2.Instead,excavatorsshouldbehandlingatleastsomeoftheirbountywithgloves,andfreezingsamplesastheyarefound,dirtandall,concludesapaperintheProceedingsoftheNationalAcademyofSciencestoday.

3.AlthoughmanypalaeontologistsknowanecdotallythatthisisthebestwaytouptheoddsofextractinggoodDNA,Eva-MariaGeigloftheJacquesMonodInstituteinParis,France,andhercolleagueshavenowshownjusthowimportantconservationpracticescanbe.Thisinformation,theysay,needstobehammeredhomeamongthepeoplewhoareactuallyoutinthefielddiggingupbones.

4.Geiglandhercolleagueslookedat3,200-year-oldfossilbonesbelongingtoasingleindividualofanextinctcattlespecies,calledanaurochs.ThefossilsweredugupatasiteinFranceattwodifferenttimes—eitherin1947,andstoredinamuseumcollection,orin2004,andconservedinsterileconditionsat-20oC.

5.Theteam'sattemptstoextractDNAfromthe1947bonesallfailed.Thenewlyexcavatedfossils,however,allyieldedDNA.

6.Becausetheboneshadbeenburiedforthesameamountoftime,andinthesameconditions,theconservationmethodhadtobetoblamesaysGeigl."AsmuchDNAwasdegradedinthese57yearsasinthe3,200yearsbefore,"shesays.

Washin,washout

7.Becausemanypalaeontologistsbasetheirworkontheshapeoffossilsalone,theirmethodsofconservationarenotdesignedtopreserveDNA,Geiglexplains.

8.Thebiggestproblemishowtheyarecleaned.Fossilsareoftenwashedtogetheron-siteinalargebath,whichcanallowwater—andcontaminantsintheformofcontemporaryDNA—topermeateintotheporousbones."NotonlyistheauthenticDNAgettingwashedout,butcontaminationisgettingwashedin,"saysGeigl.

9.MostancientDNAspecialistsknowthisalready,saysHendrikPoinar,anevolutionarygeneticistatMcMasterUniversityinOntario,Canada.Butthatdoesn'tmeanthatbestpracticehasbecomewidespreadamongthosewhoactuallyfindthefossils.

10.GettingholdoffossilsthathavebeenpreservedwiththeirDNAinmindreliesoncloserelationshipsbetweenlab-basedgeneticistsandtheexcavators,sayspalaeogeneticistSvantePbooftheMaxPlanckInstituteforEvolutionaryAnthropologyinLeipzig,Germany.Andthatonlyoccursinexceptionalcases,hesays.

11.Pbo'steam,whichhasbeensequencingNeanderthalDNA,continuallyfacestheseproblems."WhenyouwanttostudyancienthumanandNeanderthalremains,there'sabigissueofcontaminationwithcontemporaryhumanDNA,"hesays.

12.Thisdoesn'tmeanthatallmuseumspecimensarefatallyflawed,notesPbo.TheNeanderthalfossilsthatwererecentlysequencedinhisownlab,forexample,hadbeenpartofamuseumcollectiontreatedinthetraditionalway.ButPboiskeentoseesamplesoffossilsfromeverymajorfindpreservedinlinewithGeigl'srecommendations—justincase.

Warmandwet

13.Geiglherselfbelievesthat,withcooperationbetweenbenchandfieldresearchers,preservingfossilsproperlycouldopenupavenuesofdiscoverythathavelongbeenassumedclosed.

14.Muchhumanculturaldevelopmenttookplaceintemperateregions.DNAdoesnotsurvivewellinwarmenvironmentsinthefirstplace,andcanvanishwhenfossilsarewashedandtreated.Forthisreason,Geiglsays,mostancientDNAstudieshavebeendoneonpermafrostsamples,suchasthewoollymammoth,oronremainsshelteredfromtheelementsincoldcaves—includingcavebearandNeanderthalfossils.

15.Betterconservationmethods,andafocusonfreshfossils,couldboostDNAextractionfrommoredelicatespecimens,saysGeigl.Andthatcouldshedmorelightonthestoryofhumanevolution.

(640wordsnature)

Glossary

Palaeontologists古生物学家

Aurochs欧洲野牛

Neanderthal(人类学)尼安德特人，旧石器时代的古人类。

Permafrost(地理)永冻层

Questions1-6

AnswerthefollowingquestionsbyusingNOMORETHANTHREEWORDSforeachanswer.

1.Howdidpeopletraditionallytreatfossils?

2.WhatsuggestionsdoGeiglandhercolleaguesgiveonwhatshouldbedonewhenfossilsarefound?

3.Whatproblemsmaybeposediffossilbonesarewashedon-site?NameONE.

4.WhatcharacteristicdofossilboneshavetomakethemsusceptibletobecontaminatedwithcontemporaryDNAwhentheyarewashed?

5.Whatcouldbebetterunderstoodwhenconservationtreatmentsareimproved?

6.Thepassagementionedseveralanimalspeciesstudiedbyresearchers.Howmanyofthemarementioned?

Questions7-11

Dothefollowingstatementsagreewiththeinformationgiveninthepassage?PleasewriteTRUEifthestatementagreeswiththewriterFALSEifthestatementdoesnotagreewiththewriterNOTGIVENifthereisnoinformationaboutthisinthepassage.

7.IntheirpaperpublishedintheProceedingsoftheNationalAcademyofSciences，GeiglandhercolleagueshaveshownwhatconservationpracticesshouldbefollowedtopreserveancientDNA.

8.ThefossilbonesthatGeiglandhercolleaguesstudiedareallfromthesameaurochs.

9.Geneticistsdon'thavetoworkonsite.

10.OnlynewlyexcavatedfossilbonesusingnewconservationmethodssuggestedbyGeiglandhercolleaguescontainancientDNA.

11.Paaboisstillworriedaboutthepotentialproblemscausedbytreatmentsoffossilsintraditionalway.

Questions12-13

CompletethefollowingthestatementsbychoosingletterA-Dforeachanswer.

12.“Thisinformation”inparagraph3indicates:

[A]ItiscriticaltofollowproperpracticesinpreservingancientDNA.

[B]ThebestwayofgettinggoodDNAistohandlefossilswithgloves.

[C]Fossilhuntersshouldwearhome-madehammerswhilediggingupbones.

[D]Manypalaeontologistsknowhowoneshoulddointreatingfossils.

13.ThestudyconductedbyGeiglandhercolleaguessuggests:

[A]thefactthatancientDNAcannotberecoveredfromfossilbonesexcavatedinthepast.

[B]thecorrelationbetweentheamountofburyingtimeandthatoftherecoveredDNA.

[C]thepaceatwhichDNAdegrades.

[D]thecorrelationbetweenconservationpracticesanddegradationofDNA.

Roguetheoryofsmellgetsaboost

1.Acontroversialtheoryofhowwesmell,whichclaimsthatourfinesenseofodourdependsonquantummechanics,hasbeengiventhethumbsupbyateamofphysicists.

2.CalculationsbyresearchersatUniversityCollegeLondon(UCL)showthattheideathatwesmellodourmoleculesbysensingtheirmolecularvibrationsmakessenseintermsofthephysicsinvolved.

3.That'sstillsomewayfromprovingthatthetheory,proposedinthemid-1990sbybiophysicistLucaTurin,iscorrect.Butitshouldmakeotherscientiststaketheideamoreseriously.

4."Thisisabigstepforward,"saysTurin,whohasnowsetuphisownperfumecompanyFlexitralinVirginia.Hesaysthatsincehepublishedhistheory,"ithasbeenignoredratherthancriticized."

5.Mostscientistshaveassumedthatoursenseofsmelldependsonreceptorsinthenosedetectingtheshapeofincomingmolecules,whichtriggersasignaltothebrain.Thismolecular'lockandkey'processisthoughttoliebehindawiderangeofthebody'sdetectionsystems:itishowsomepartsoftheimmunesystemrecogniseinvaders,forexample,andhowthetonguerecognizessometastes.

6.ButTurinarguedthatsmelldoesn'tseemtofitthispictureverywell.Moleculesthatlookalmostidenticalcansmellverydifferent—suchasalcohols,whichsmelllikespirits,andthiols,whichsmelllikerotteneggs.Andmoleculeswithverydifferentstructurescansmellsimilar.Moststrikingly,somemoleculescansmelldifferent—toanimals,ifnotnecessarilytohumans—simplybecausetheycontaindifferentisotopes(atomsthatarechemicallyidenticalbuthaveadifferentmass).

7.Turin'sexplanationforthesesmellyfactsinvokestheideathatthesmellsignalinolfactoryreceptorproteinsistriggerednotbyanodourmolecule'sshape,butbyitsvibrations,whichcanenourageanelectrontojumpbetweentwopartsofthereceptorinaquantum-mechanicalprocesscalledtunnelling.Thiselectronmovementcouldinitiatethesmellsignalbeingsenttothebrain.

8.Thiswouldexplainwhyisotopescansmelldifferent:theirvibrationfrequenciesarechangediftheatomsareheavier.Turin'smechanism,saysMarshallStonehamoftheUCLteam,ismorelikeswipe-cardidentificationthanakeyfittingalock.

9.Vibration-assistedelectrontunnellingcanundoubtedlyoccur—itisusedinanexperimentaltechniqueformeasuringmolecularvibrations."Thequestioniswhetherthisispossibleinthenose,"saysStoneham'scolleague,AndrewHorsfield.

10.StonehamsaysthatwhenhefirstheardaboutTurin'sidea,whileTurinwashimselfbasedatUCL,"Ididn'tbelieveit".But,headds,"becauseitwasaninterestingidea,IthoughtIshouldproveitcouldn'twork.Ididsomesimplecalculations,andonlythenbegantofeelLucacouldberight."NowStonehamandhisco-workershavedonethejobmorethoroughly,inapapersoontobepublishedinPhysicalReviewLetters.

11.TheUCLteamcalculatedtheratesofelectronhoppinginanosereceptorthathasanodorantmoleculeboundtoit.Thisratedependsonvariouspropertiesofthebiomolecularsystemthatarenotknown,buttheresearcherscouldestimatetheseparametersbasedontypicalvaluesformoleculesofthissort.

12.Thekeyissueiswhetherthehoppingratewiththeodorantinplaceissignificantlygreaterthanthatwithoutit.Thecalculationsshowthatitis—whichmeansthatodouridentificationinthiswayseemstheoreticallypossible.

13.ButHorsfieldstressesthatthat'sdifferentfromaproofofTurin'sidea."Sofarthingslookplausible,butweneedproperexperimentalverification.We'rebeginningtothinkaboutwhatexperimentscouldbeperformed."

14.Meanwhile,Turinispressingaheadwithhishypothesis."AtFlexitralwehavebeendesigningodorantsexclusivelyonthebasisoftheircomputedvibrations,"hesays."Oursuccessrateatodorantdiscoveryistwoordersofmagnitudebetterthanthecompetition."Attheveryleast,heisputtinghismoneywherehisnoseis.

Questions5-9

Completethesentencesbelowwithwordsfromthepassage.UseNOMORETHANTHREEWORDSforeachanswer.

5.Thehypothesisthatwesmellbysensingthemolecularvibrationwasmadeby______.

6.Turin'scompanyisbasedin______.

7.Mostscientistsbelievedthatournoseworksinthesamewayasour______.

8.Differentisotopescansmelldifferentwhen______weighdifferently.

9.AccordingtoAudrewHorsfield,itisstilltobeprovedthat______couldreallyoccurinhumannose.

ReadingComprehension

SectionA

Directions:Therearetenincompletesentencesinthissection.ForeachsentencetherearefourchoicesmarkedA,B,CandD.ChoosetheONEthatbestcompletesthesentence.Thenwritedowntherightanswerinthebracketsforeachsentence.Thissectiontotals10points,onepointforeachsentence.

()1.Wecansupplyallthebicyclesyourequired____________stockandarearrangingshipmentbyM.V.Mermaid.

A.forB.from　C.to　D.against

()2.Wewouldliketoremindyouthatthe__________L/CmustreachusbeforeMarch10

sothatwecanmakeshipmentingoodtime.

A.coveringB.cover　C.coveredD.beingcovered

()3.Wehavereceivedyourletterof28March,___________ustomodifythepreviousarrangementsfortheshipmentofthecaptionedorder.

A.askedB.toask　C.beingaskedD.asking

()4.InourletterofMay5,wemade__________clearthatshipmentistobeeffectedinJune.

A.youB.them　C.thatD.it

()5.Wealwaysdeal_______________paymentbysightL/C.

A.with　B.in　C.at　D.on

()6.Thisofferis_____________toyourreplyreachingusbeforethe20thofFebruary.

A.subjectingB.subject　C.subjectedDtosubject

()7.____________weareappreciatingthegoodqualityofyourblacktea,weregretthatyourpriceappearstobeonthehighside.

A.WhileB.When　C.HoweverD.Therefore

()8.Weherebyauthorizeyouto___________onusat60daysaftersighttotheextentofUSD20,000.00.

A.open　B.establish　C.draw　D.build

()9.Ifpartiestoacontractdesiretosettledisputes,anarbitrationclauseisusuallymadeinthecontractwellbeforeadispute_____________.

A.risesB.arisesC.lookD.appear

()10.Somecustomersrequestedusto_____________ourpricebecausetheyconsideredit

toohigh.

A.putdownB.getdownC.takedown　D.bringdown

Bodylanguagealsocalled: